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AACE

Patients With Type 2 Diabetes and CKD Face Poor COVID Outcomes

Severity of kidney disease ups risk of ICU time, in-hospital mortality, and more

Investigational Liver Drug Also Effective in Patients With Hypothyroidism

"This is yet another reason endocrinologists should get involved in fatty liver disease"

Tymlos Boosts Bone Health in Men With Osteoporosis

Daily agent upped bone mineral density at multiple sites in phase III ATOM trial

Heart Risk With Gender-Affirming Tx; Burden of Thyroid Eye Disease; T1D Care Gaps

More notable research from the AACE 2021 virtual meeting

Patients With Underactive Thyroid Report Pervasive Brain Fog

Many said they had symptoms well before a hypothyroidism diagnosis

High Frequency Spinal Stimulation Succeeds in Diabetic Neuropathy

Pain relief was significant and durable in SENZA-PDN trial

Two-Agent Osteoporosis Treatment Boosts BMD

3D DXA images shows separate assessments of trabecular and cortical bone in ACTIVExtend trial

COVID-19 in Diabetes: What Mediates Risk?

Certain clinical factors tied to higher chance of severe infection

Slow and Steady With Osilodrostat Best in Cushing's Disease

Gradual dose escalation had fewer adverse events, same therapeutic benefit, as quicker increases

Improvements in Excess Cortisol Activity With Relacorilant

Phase II study of selective glucocorticoid receptor modulator found dose-dependent effect

Novel Agent Reduces Bulging Eyes in Thyroid Eye Disease

Results with teprotumumab in phase III trial called "watershed moment"

PET Imaging Top Choice for Detecting Parathyroid Adenomas

Study compared method to two other techniques

AACE 2018 Potpourri

Additional noteworthy research presented at AACE meeting

Carvedilol Helps Protect Heart During PPGL Surgery

Med offers superior blocking for cardiac complications in pheochromocytoma

Better Specificity with Next-Gen Thyroid Gene Sequence Test

Afirma GSC seems to send fewer patients for surgical intervention

Thyroid Nodule Location Predictive of Malignancy

Nodules in the upper pole more likely to be cancerous

Hypogonadal Men See Better Heart Health on Testosterone Tx

Fewer deaths due to MACE seen over 10 years versus controls

Dapagliflozin Tied to Drop in Hepcidin Levels

Decrease may boost hematocrit and hemoglobin after SGLT-2 inhibitor therapy

Early Use of Burosumab Eases XLH Symptoms in Kids

Treatment improved rickets severity, serum phosphorus, and calcitriol levels

Low PTH-Calcium Ups Risk for Long-Term Parathyroid Problems

Levels help guide patient management after thyroidectomy

Risk Factors for Ipilimumab-Induced Hypophysitis Remain Unclear

Researchers recommend close monitoring of these patients

AACE 2018: Setting a Course for Endocrinology's Future

Annual meeting highlights include new obesity treatments, nutrition medicine, intensive T2D management

Serum Ferritin, Iron Linked to A1c in Uncontrolled T2D

Iron indices may act as surrogate markers

Improved T2D Outcomes Predicted with Electronic Registry

Researchers hope to use as tool for overcoming barriers to care

A1c Improved With Switch to 24-Hour Insulin Pump

Wearable insulin delivery system associated with reductions in glycemic levels in type 2 diabetics

Euthyroid Achievement Possible With Once-Weekly L-Thyroxine

Most patients normalized thyroid function with 12 weeks of higher dose

Radiation Tx for Persistent Acromegaly Safe, Effective

Helped normalize IGF-1 levels after surgery failed

Should Repeat FNA for Thyroid Nodules Again Be Recommended?

A systematic review and meta-analysis reported a 98% NPV for repeat FNA

AACE: 2017 Meeting Highlights Innovation

Presentations on novel insulin systems, immunotherapy

Canagliflozin Leads to Better A1c Control

Post-hoc analysis also finds lower risk of hypoglycemia

Combo Tx Leads to Better Outcomes for Hypothyroidism

T3-T4 therapy improves symptoms, boosts quality of life

Bariatric Surgery Improves Metabolic Syndrome for PCOS

Small cohort with obesity and PCOS saw improvement

Radiofrequency Ablation Works for Adrenal Tumor

"Drastic clinical improvement" seen at 7 months

Man With Micropenis Responds to Testosterone

Therapy helps Kallmann syndrome patient

Obesity Is a Chronic Disease, Say New Guidelines

AACE's evidence-based guidelines aims to help physicians

Obesity Guidelines Headline AACE 2016

First such guidelines in 25 year history

GI Events Do Not Explain Weight Loss With Saxenda

No difference in weight loss between patients who had nausea and vomiting with diet drug, and those who didn't.

Three Diabetes Drugs Linked to Ketoacidosis, FDA Warns

FDA targets SGLT2 inhibitors canagliflozin, dapagliflozin, and empagliflozin.

'Bulletproof' Coffee May Hike Lipids

LAS VEGAS -- Spiking coffee with butter and coconut oil -- a concoction known as "bulletproof coffee" -- may be boosting hyperlipidemia in otherwise healthy patients, researchers said here.

'Thyroid' Issues May Really Be Hypothalamic

LAS VEGAS -- Obese patients who continue to have "thyroid symptoms" even when their levels are normalized may have a hypothalamic dysfunction, researchers reported here.

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